Thursday, April 10, 2014

Aggregation of Therapeutic Proteins


Aggregation of Therapeutic Proteins [Format Kindle]

Author: Wei Wang Christopher J. Roberts | Language: English | ISBN: B0052NGJDC | Format: PDF, EPUB

Aggregation of Therapeutic Proteins
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Revue de presse

"Among their topics are fundamental structures and behaviors of proteins; protein aggregation pathways, kinetics, and thermodynamics; the identification and impact of aggregate–prone regions in proteins and therapeutic monoclonal antibodies; external factors affecting protein aggregation; experimental detection and characterization of protein aggregates; approaches to controlling it during bulk production; effects of formulation interfaces, and drug product manufacturing operations on aggregation and particle formation; approaches to managing it in product development; aggregation and immunogenicity of therapeutic proteins; and a regulatory perspective on aggregates as a product quality attribute." ( SciTech Book News, December 2010)

Présentation de l'éditeur

This book gives pharmaceutical scientists an up-to-date resource on protein aggregation and its consequences, and available methods to control or slow down the aggregation process. While significant progress has been made in the past decade, the current understanding of protein aggregation and its consequences is still immature. Prevention or even moderate inhibition of protein aggregation has been mostly experimental. The knowledge in this book can greatly help pharmaceutical scientists in the development of therapeutic proteins, and also instigate further scientific investigations in this area. This book fills such a need by providing an overview on the causes, consequences, characterization, and control of the aggregation of therapeutic proteins.
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Détails sur le produit

  • Format : Format Kindle
  • Taille du fichier : 3609 KB
  • Nombre de pages de l'édition imprimée : 484 pages
  • Editeur : Wiley; àdition : 1 (18 mai 2011)
  • Vendu par : Amazon Media EU S.à r.l.
  • Langue : Anglais
  • ASIN: B0052NGJDC
  • Synthèse vocale : Activée
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    Aggregation of Therapeutic Proteins 9780470411964 Understanding and controlling protein aggregation The growth of therapeutic proteins as candidates in drug development pipelines is progressing at a record speed Aggregation of Therapeutic Proteins Wiley Online Library This book gives pharmaceutical scientists an up to date resource on protein aggregation and its consequences and available methods to control or Aggregation of Therapeutic Proteins Google Books This book gives pharmaceutical scientists an up to date resource on protein aggregation and its consequences and available methods to control or slow down Aggregation of Therapeutic Proteins Kindle edition by Aggregation of Therapeutic Proteins Kindle edition by Wei Wang Christopher J Roberts Download it once and read it on your Kindle device PC phones or tablets Wiley Aggregation of Therapeutic Proteins Wei Wang Preface Contributors 1 Fundamental Structures and Behaviors of Proteins Jennifer S Laurence and C Russell Middaugh 1 1 The Problem of Protein Aggregation
    Excellent coverage and in depth discussion. So far, this is the best book on the subject.
    Par A. T. Barry
    - Publié sur Amazon.com

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